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The compound is a synthetic peptide fragment corresponding to amino acids 177-191 of the C-terminal region of human growth hormone, modified with an added tyrosine residue at the N-terminus

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pulsatility” as well as “sustained, dose-dependent increases in [growth hormone] and IGF-I levels in healthy adults.”11 9 In 1999, a human trial with 40 total volunteers concluded that ipamorelin at multiple doses induces growth hormone secretion at sufficient levels to be biologically effective, with peak concentration arriving within an hour.12 These studies examined the two peptides separately, but their results validate the mechanisms of action that underlie the reason that CJC-1295 and ipamorelin are used together